Invention Grant
- Patent Title: Compositions of active Wnt protein
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Application No.: US14966930Application Date: 2015-12-11
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Publication No.: US09725696B2Publication Date: 2017-08-08
- Inventor: Roeland Nusse , Karl H. Willert
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K38/16 ; C12N5/074 ; C07K14/47 ; C12N5/0789 ; C07K14/575
Abstract:
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
Public/Granted literature
- US20160097031A1 Compositions of Active WNT Protein Public/Granted day:2016-04-07
Information query
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