Invention Grant
- Patent Title: Modulation of TMPRSS6 expression
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Application No.: US14356863Application Date: 2012-11-07
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Publication No.: US09725722B2Publication Date: 2017-08-08
- Inventor: Shuling Guo
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Ionis Pharmaceuticals, Inc. Patent Dept.
- International Application: PCT/US2012/063970 WO 20121107
- International Announcement: WO2013/070786 WO 20130516
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K31/713 ; A61K45/06 ; C12N5/00
Abstract:
Disclosed herein are antisense compounds and methods for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an individual in need thereof. Iron accumulation diseases in an individual such as hemochromatosis or β-thalassemia can be ameliorated or prevented with the administration of antisense compounds targeted to TMPRSS6.
Public/Granted literature
- US20140309286A1 MODULATION OF TMPRSS6 EXPRESSION Public/Granted day:2014-10-16
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