Invention Grant
- Patent Title: Compositions and methods for modulation of FGFR3 expression
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Application No.: US14647430Application Date: 2013-11-25
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Publication No.: US09725723B2Publication Date: 2017-08-08
- Inventor: Maj Hedtjarn , Soren Ottosen
- Applicant: ROCHE INNOVATION CENTER COPENHAGEN A/S
- Applicant Address: DK Hoersholm
- Assignee: Roche Innovation Center Copenhagen A/S
- Current Assignee: Roche Innovation Center Copenhagen A/S
- Current Assignee Address: DK Hoersholm
- Agency: Fish & Richardson P.C.
- International Application: PCT/EP2013/074552 WO 20131125
- International Announcement: WO2014/080004 WO 20140530
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/11 ; C12N15/113
Abstract:
Disclosed are oligonucleotides which target and hybridize to nucleic acid molecules encoding FGFR3, leading to reduced expression of FGFR3. Reduction in the aberrant expression of FGFR3 is beneficial for the treatment of certain medical disorders, such as achondroplasia.
Public/Granted literature
- US20150307886A1 COMPOSITIONS AND METHODS FOR MODULATION OF FGFR3 EXPRESSION Public/Granted day:2015-10-29
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