Invention Grant
- Patent Title: Treatment of ‘C terminus of HSP7O-interacting protein’ (CHIP) related diseases by inhibition of natural antisense transcript to CHIP
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Application No.: US14297010Application Date: 2014-06-05
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Publication No.: US09725756B2Publication Date: 2017-08-08
- Inventor: Joseph Collard , Olga Khorkova Sherman , Carlos Coito
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12Q1/68 ; A61K31/7088 ; C12N15/113
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of ‘C terminus of HSP70-Interacting Protein’ (CHIP), in particular, by targeting natural antisense polynucleotides of ‘C terminus of HSP70-Interacting Protein’ (CHIP). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of CHIP.
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