Invention Grant
- Patent Title: Device and method for producing a replicate or derivative from an array of molecules, and applications thereof
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Application No.: US13224645Application Date: 2011-09-02
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Publication No.: US09725758B2Publication Date: 2017-08-08
- Inventor: Roland Zengerle , Felix Von Stetten , Guenter Roth , Jochen Hoffmann
- Applicant: Roland Zengerle , Felix Von Stetten , Guenter Roth , Jochen Hoffmann
- Applicant Address: DE Freiburg
- Assignee: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
- Current Assignee: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
- Current Assignee Address: DE Freiburg
- Agency: Agris & von Natzmer LLP
- Agent Joyce von Natzmer
- Priority: DE102009012169 20090306
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; B01J19/00 ; C12Q1/48

Abstract:
A method of producing a replicate or derivative of an array of molecules, the array having a spatial arrangement of separate samples of molecules, includes creating, for each sample, at least one spatially limited effective area which is separate from the effective areas of the other samples, a surface, provided with a binding adapter or binding properties, of a carrier bordering on the effective areas. The molecules are amplified by means of amplifying agents in the effective areas for creating replicates or derivatives of the samples. The replicates or derivatives of the samples are bound to the carrier by means of the binding adapter or the binding properties, so that a spatial arrangement of the replicates or derivatives of the samples on the carrier corresponds to the spatial arrangement of the samples in the array. The carrier having the copies of the samples is removed from the array.
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