An unlocking method and an electronic device are provided. The method is suitable for the electronic device having a touch screen and being in a screen lock mode. The method includes: displaying a first region and a second region on the touch screen; adjusting the first region and the second region according to a tilting state of the electronic device; receiving a touch operation performed on the touch screen; and switching the electronic device to an unlock mode when the touch operation starts in the first region and ends in the second region.