A method of operating a touch screen sensor integrated circuit includes: receiving a plurality of current signals through a plurality of pins, wherein each current signal is generated according to mutual capacitance in response to a modulation signal; sensing the current signals and generating a plurality of sensed current signals corresponding to each of the current signals; and generating a plurality of subtracted current signals, wherein each subtracted current signal is generated by performing a subtraction on sensed current signals corresponding to a pair of the pins.