Systems and methods are provided to schedule clinical tasks involving multiple sub-tasks and multiple resources in a clinical enterprise. An example method includes identifying a slot for a task defined by a task duration and one or more resources, the task including a plurality of sub-tasks, each sub-task having a sub-task duration utilizing one or more of the one or more resources, wherein each sub-task to be performed consecutively based on resource constraints; selecting a time slot for the task based on resource availability, the plurality of sub-tasks in the task, and a duration associated with each sub-task, wherein resource availability information is obtained from a clinical information system, and wherein each resource is scheduled only for one or more sub-tasks in which the resource is involved; displaying the schedule including the task and the plurality of sub-tasks; and facilitating access to view and modify the schedule.