The present invention provides an AMOLED pixel driving circuit and a pixel driving method. The AMOLED pixel driving circuit utilizes a 5T1C structure, comprising a first, a second, a third, a fourth and a fifth thin film transistors (T1, T2, T3, T4, T5), a capacitor (C) and an organic light emitting diode (OLED). The first thin film transistor (T1) is a drive thin film transistor; the first global signal (G1), the second global signal (G2) and the scan signal (Scan) are introduced to be combined with one another, and correspond to an initialization stage (1), a data writing stage (2), a threshold voltage compensation stage (3) and a drive stage (4) one after another, wherein the data writing stage (2) and the threshold voltage compensation stage (3) are simultaneously proceeded for effectively compensating the threshold voltage variations of the drive thin film transistor and the organic light emitting diode to make the display brightness of the AMOLED more even and to promote the display quality.