To maximize efficiencies and to reduce termination costs of inter-carrier exchanges, an auto-dialer detection system enables an inter-carrier network switch to detect, in real-time or in near real-time, calls that are originated by auto-dialers. A call router of the switch may receive an incoming call attempt that includes a particular Automatic Number Identification (ANI). The auto-dialer detection system allows for a real-time or near-real time determination, based on the ANI and contents of a cache during a sliding window of time coincident with the reception of the origination, whether or not the call should be routed through the switch. Further, the auto-dialer detection system provides a real-time or a near real-time update to the cache contents to enable further real-time or near-real time detection and blocking of auto-dialed calls. Overrides to the cache (e.g., to always allow and/or to always block calls that include certain ANIs) may be provided.