Systems and methods for providing enhancement of upload and/or download performance based on client and/or server feedback information are disclosed. In one embodiment, the disclosed method optimizes upload performance by performing an upload speed test to measure an upload speed associated with each of multiple servers. The method detects a user request to upload a file from a client device to a host server. Based on results from the upload speed test, the method selects one of the multiple servers to upload the file. The multiple servers can include host servers providing cloud-based collaboration and/or storage services, one or more content delivery network servers and/or geographically distributed edge servers.