Invention Grant
- Patent Title: Cinnoline derivatives useful as CB-1 receptor inverse agonists
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Application No.: US14992464Application Date: 2016-01-11
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Publication No.: US09732061B2Publication Date: 2017-08-15
- Inventor: Mark Joseph Macielag , Yue-Mei Zhang , Bart L. DeCorte , Michael N. Greco , Donald W. Ludovici , Michael H. Parker
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Thomas J. Dodd
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D409/14 ; C07D405/14 ; C07D417/14 ; C07D401/04 ; C07D403/12 ; C07D237/28
Abstract:
The present invention is directed to cinnoline derivatives pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.
Public/Granted literature
- US20160200719A1 CINNOLINE DERIVATIVES USEFUL AS CB-1 RECEPTOR INVERSE AGONISTS Public/Granted day:2016-07-14
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