A vacuum cleaner assembly designed for use in a vehicle having a passenger compartment such as those with at least one row of seats and a cargo area. The vacuum cleaner assembly preferably includes a power head, a collection drum or other container, and a hose. The powerhead of the present invention is powered by the vehicle's electrical system and is preferably mounted between exterior body panels and interior compartment panels of the vehicle. For example, the power head may be mounted between the exterior body panels and the interior compartment panels adjacent to, but not in the cargo area.