- 专利标题： Aryl sultam derivatives as RORc modulators
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申请号： US15047523申请日： 2016-02-18
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公开(公告)号： US09751873B2公开(公告)日： 2017-09-05
- 发明人: Benjamin Fauber , Alberto Gobbi , Olivier Rene , Monique Bodil van Niel , Emanuela Gancia , Simon Gaines , Tammy Ladduwahetty , David Vesey , Stuart Ward , Paul Winship
- 申请人： Genentech, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理商 Robert C. Hall
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; C07D417/10 ; C07D279/02 ; C07D417/12 ; C07D491/107 ; C07D491/113 ; C07D487/08
摘要：
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
公开/授权文献
- US20160168141A1 ARYL SULTAM DERIVATIVES AS RORc MODULATORS 公开/授权日：2016-06-16
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