- 专利标题: Diaryl[A, G]quinolizidine compound, preparation method therefor, pharmaceutical composition, and uses thereof
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申请号: US14400203申请日: 2013-05-09
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公开(公告)号: US09751882B2公开(公告)日: 2017-09-05
- 发明人: Hong Liu , Xuechu Zhen , Haifeng Sun , Liyuan Zhu , Wangke Qian , Leiping Yu , Zeng Li , Shengbin Zhou , Wenxian Cai , Hualiang Jiang , Kaixian Chen
- 申请人: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 申请人地址: CN Beijing
- 专利权人: Kingsound & Partner
- 当前专利权人: Kingsound & Partner
- 当前专利权人地址: CN Beijing
- 代理机构: Andrews Kurth Kenyon LLP
- 代理商 Ping Wang
- 优先权: CN201210142903 20120509
- 国际申请: PCT/CN2013/000549 WO 20130509
- 国际公布: WO2013/166862 WO 20131114
- 主分类号: C07D471/14
- IPC分类号: C07D471/14 ; C07D495/14 ; C07D491/22 ; C07D491/147 ; C07D495/22 ; C07D455/03
摘要:
The present invention relates to a diarylo[a,g]quinolizidine compound of formula (I), enantiomer, diastereoisomer, racemate, mixture, pharmaceutically acceptable salt, crystalline hydrate or solvate thereof; the preparation method thereof, and uses thereof in preparing an experimental model drugs related to dopamine receptors and 5-HT receptors or a medicament for treating or preventing a disease related to dopamine receptors and 5-HT receptors.
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