![Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof](/docs/US/2017-09-05/US09751883B2/abs.jpg.600x600.jpg)
- Patent Title: Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof
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Application No.: US15066962Application Date: 2016-03-10
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Publication No.: US09751883B2Publication Date: 2017-09-05
- Inventor: John Charles Tomesch , Peng Li , Wei Yao , Qiang Zhang , James David Beard , Andrew S. Thompson , Hua Cheng , Lawrence P. Wennogle
- Applicant: Intra-Cellular Therapies, Inc.
- Applicant Address: US NY New York
- Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee Address: US NY New York
- Agency: Hoxie & Associates LLC
- Main IPC: C07D487/22
- IPC: C07D487/22 ; C07D471/22 ; C07D471/16 ; C07D471/04
![Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof](/abs-image/US/2017/09/05/US09751883B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines of Formula 2J, as shown below, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines, such methods comprising the preparation of a Compound of Formula 2G, as shown below, and use of said compound to produce the fused gamma-carbolines of Formula 2J, as defined herein:
Public/Granted literature
- US20160194326A1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS Public/Granted day:2016-07-07
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