- 专利标题: Edible and animal-product-free microcarriers for engineered meat
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申请号: US14486850申请日: 2014-09-15
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公开(公告)号: US09752122B2公开(公告)日: 2017-09-05
- 发明人: Francoise Suzanne Marga , Brendan Patrick Purcell , Gabor Forgacs , Andras Forgacs
- 申请人: Modern Meadow, Inc.
- 申请人地址: US NY Brooklyn
- 专利权人: Modern Meadow, Inc.
- 当前专利权人: Modern Meadow, Inc.
- 当前专利权人地址: US NY Brooklyn
- 代理机构: Oblon, McClelland, Maier & Neustadt, L.L.P.
- 主分类号: C12N5/077
- IPC分类号: C12N5/077 ; A23P10/20 ; A23L13/00
摘要:
Edible microcarriers, including microcarrier beads, microspheres and microsponges, appropriate for use in a bioreactor to culture cells that may be used to form a comestible engineered meat product. For example, the edible microcarriers described herein may include porous microcarriers that may be used to grow cells (e.g., smooth muscle cells) and may be included with the cells in the final engineered meat product, without requiring modification or removal of the cells from the microcarriers. In a particular example, the edible microcarriers may be formed of cross-linked pectin, such as pectin-thiopropionylamide (PTP), and RGD-containing polypeptide, such as thiolated cardosin A. Methods of forming edible microcarriers, methods of using the edible microcarriers to make engineered meat, and engineered meat including the edible microcarriers are also described herein.