Invention Grant
- Patent Title: IDO inhibitors
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Application No.: US14914184Application Date: 2014-08-26
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Publication No.: US09758492B2Publication Date: 2017-09-12
- Inventor: Jay A. Markwalder , Steven P. Seitz , James Aaron Balog , Audris Huang , Sunil Kumar Mandal , Shefali Srivastava , David K. Williams , Libing Chen
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton IN Bommasandra, Bangalore US NJ Princeton
- Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Syngene International Limited
- Current Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Syngene International Limited
- Current Assignee Address: US NJ Princeton IN Bommasandra, Bangalore US NJ Princeton
- Agent Serena Farquharson-Torres; Maureen S. Gibbons
- International Application: PCT/US2014/052600 WO 20140826
- International Announcement: WO2015/031295 WO 20150305
- Main IPC: C07D257/04
- IPC: C07D257/04 ; A61K31/17 ; A61K31/18 ; A61K31/381 ; A61K31/41 ; A61K31/422 ; A61K31/427 ; A61K31/4439 ; A61K31/451 ; A61K31/4709 ; A61K31/497 ; A61K31/50 ; A61K31/506 ; A61K31/5375 ; A61K45/06 ; C07D211/14 ; C07D237/20 ; C07D333/38 ; C07D401/10 ; C07D407/12 ; C07D417/12 ; C07D403/12 ; C07D309/14 ; C07D215/06 ; C07D231/12 ; C07D333/10 ; C07D401/12 ; C07D409/12 ; C07D411/12 ; C07D413/12 ; C07D277/22 ; C07C275/42 ; C07C311/05 ; C07C311/09 ; C07C317/44 ; C07B59/00
Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or autoimmune diseases utilizing the compounds of the invention.
Public/Granted literature
- US20160200674A1 IDO INHIBITORS Public/Granted day:2016-07-14
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