A centrifugal moisture removal device includes a rotating mechanism and a fixing mechanism. The rotating mechanism includes a rotating bracket and a rotary driving member. The rotating bracket includes two sleeving portions. The fixing mechanism includes two positioning members, two clamping members, and two line driving members. Each clamping member includes a moving staff, an elastic member, and a sensing member. A first end portion of the moving staff passes through a sleeving portion and is mounted on a positioning member. The elastic member is sleeved on the moving staff. A first end portion of the elastic member resists the sleeving portion. A second end portion of the elastic member resists a second end portion of the moving staff. Each line driving member is set above the second end portion of a moving staff. The sensing member senses when the workpiece arrives at the positioning member.