A method and device for determining available spectrums is disclosed in embodiments of the present invention. By applying the technical solution of the embodiments of the present invention, with consideration on the bi-directionality of the interference between wireless communication systems, when introduction of the cognitive system is required, the corresponding frequency will be determined as an available frequency only in the case the incumbent system and the cognitive system can be simultaneously guaranteed to meet the corresponding coexistence criterion among the corresponding frequency and adjacent frequencies thereof, thus ensuring that the determined available frequency band guarantees that the normal operation of the incumbent system is not interfered by the cognitive system while ensuring that the newly-introduced cognitive system can also operate normally without interference of the incumbent system, thereby improving the communication quality of the wireless communication systems.