- 专利标题： Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them
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申请号： US14905877申请日： 2014-07-22
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公开(公告)号： US09765056B2公开(公告)日： 2017-09-19
- 发明人: Patrick Casara , Thierry Le Diguarher , Jean-Michel Henlin , Jéröme-Benoit Starck , Arnaud Le Tiran , Guillaume De Nanteuil , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen , Claire Walmsley , Christopher John Graham , Stuart Ray , Daniel Maddox , Simon Bedford
- 申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD
- 申请人地址： FR Suresnes GB Winnersh
- 专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人地址： FR Suresnes GB Winnersh
- 代理机构： Hueschen and Sage
- 优先权： FR1357277 20130723
- 国际申请： PCT/FR2014/051884 WO 20140722
- 国际公布： WO2015/011396 WO 20150129
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D401/10 ; C07D401/14 ; C07D405/14 ; A61K31/4709 ; C07D471/04 ; A61K45/06 ; A61K31/4725 ; A61K31/496 ; A61K31/5377 ; C07D409/14
摘要：
Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
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