Invention Grant
- Patent Title: Antibodies to carcinoembryonic antigen-related cell adhesion molecule (CEACAM)
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Application No.: US14350970Application Date: 2012-10-10
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Publication No.: US09771431B2Publication Date: 2017-09-26
- Inventor: Gal Markel , Tehila Ben Moshe , Yair Sapir , Ilana Mandel , Jacob Schachter , Rona Ortenberg
- Applicant: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. , CCAM BIOTHERAPEUTICS LTD. , RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Applicant Address: IL Hod Hasharon
- Assignee: CCAM BIOTHERAPEUTICS LTD.
- Current Assignee: CCAM BIOTHERAPEUTICS LTD.
- Current Assignee Address: IL Hod Hasharon
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: WOPCT/IL2011/000808 20111011
- International Application: PCT/IL2012/050402 WO 20121010
- International Announcement: WO2013/054331 WO 20130418
- Main IPC: C07K16/42
- IPC: C07K16/42 ; C07K16/30 ; A61K35/17 ; A61K39/395 ; A61K45/06 ; G01N33/68 ; A61K39/00
Abstract:
The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing a specific epitope of the protein CEACAM1 and optionally binds also other subtypes of the CEACAM protein family. Disclosed antibodies and antibody fragments are characterized by specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
Public/Granted literature
- US20140271618A1 ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE (CEACAM) Public/Granted day:2014-09-18
Information query
