The present disclosure discloses a composite film and a method for manufacturing the same, and an organic light-emitting diode and a method for packaging the same. The composite film comprises: a base membrane; a PDDA layer, which is deposited on a first surface of the base membrane; a graphite oxide layer, which is deposited on the PDDA layer; a monomolecular layer, which is self-assembled on a surface of the graphite oxide layer and is composed of a compound of Formula I. The method for manufacturing the composite film comprises a self-assembling step which includes placing and soaking a base membrane deposited with a graphite oxide layer in a solution of a compound of Formula I, and self-assembling the compound of Formula I on the graphite oxide layer.