Invention Grant
- Patent Title: Bicyclic sulfonamide compounds as sodium channel inhibitors
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Application No.: US14898070Application Date: 2014-06-11
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Publication No.: US09776995B2Publication Date: 2017-10-03
- Inventor: Matthew Weiss , Erin F. DiMauro , Thomas Dineen , Russell Graceffa , Angel Guzman-Perez , Hongbing Huang , Charles Kreiman , Isaac E. Marx , Hanh Nho Nguyen , Emily Anne Peterson , Holly L. Deak
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- International Application: PCT/US2014/041998 WO 20140611
- International Announcement: WO2014/201173 WO 20141218
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D471/04 ; C07D413/12 ; C07D401/12 ; C07D413/14 ; C07D417/12 ; C07C53/18 ; C07D215/227 ; C07D403/12 ; C07D215/36 ; C07D241/44 ; C07D401/14
Abstract:
The present invention provides compounds of Formula I or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
Public/Granted literature
- US20160137636A1 Bicyclic Sulfonamide Compounds as Sodium Channel Inhibitors Public/Granted day:2016-05-19
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