- 专利标题: Amino-substituted imidazopyridazines
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申请号: US14388940申请日: 2013-03-27
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公开(公告)号: US09777004B2公开(公告)日: 2017-10-03
- 发明人: Knut Eis , Florian Puehler , Ludwig Zorn , Volker Schulze , Detlev Sülzle , Philip Lienau , Andrea Hägebarth , Kirstin Petersen , Ulf Bömer
- 申请人: Bayer Intellectual Property GmbH
- 申请人地址: DE Monheim
- 专利权人: BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人: BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人地址: DE Monheim
- 代理机构: Nixon & Vanderhye P.C.
- 优先权: EP12162037 20120329
- 国际申请: PCT/EP2013/056488 WO 20130327
- 国际公布: WO2013/144189 WO 20131003
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/5025 ; A61K31/5377
摘要:
The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I), in which A, R1, R2, R3, R4, R5 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
公开/授权文献
- US20150087631A1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES 公开/授权日:2015-03-26
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