Systems and methods for active noise reduction and occlusion reduction based on seal quality of an in-the-ear (ITE) module inserted into a user's ear canal are provided. An example method includes receiving one or more acoustic signals. Each of the acoustic signals represents at least one captured sound having at least one of a voice component and an unwanted noise. The voice component may include the user's own voice. A quality of a seal of an ear canal is determined based at least partially on the acoustic signals. If the quality of the seal exceeds a predetermined threshold value, an occlusion reduction is performed on the acoustic signals to improve the voice component. If the quality of the seal is below a predetermined threshold value, active noise reduction is performed on the acoustic signals to reduce the unwanted noise.