A hybrid memory system includes a primary memory comprising a host memory space arranged as memory sectors corresponding to host logical block addresses (host LBAs). A secondary memory is implemented as a cache for the primary host memory. A hybrid controller is configured directly map the clusters of host LBAs to clusters of secondary memory. The secondary memory clusters correspond to a memory space of the cache. Mapping of the host LBA secondary memory clusters is fully associative such that any host LBA cluster can be mapped to any secondary memory cluster.