- 专利标题: Immediate release film coatings containing medium chain glycerides and substrates coated therewith
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申请号: US15332319申请日: 2016-10-24
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公开(公告)号: US09789067B2公开(公告)日: 2017-10-17
- 发明人: Jason Teckoe , Bradley J. Prusak , Jeffrey R. Gimbel , Daniel To
- 申请人: BPSI Holdings, LLC
- 申请人地址: US DE Wilmington
- 专利权人: BPSI Holdings, LLC
- 当前专利权人: BPSI Holdings, LLC
- 当前专利权人地址: US DE Wilmington
- 代理机构: Lucas & Mercanti, LLP
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/28
摘要:
The present invention is directed to immediate release film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain medium chain glycerides as detackifiers. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat. In preferred aspects, the polymer is polyvinyl alcohol and the medium chain glycerides are mixtures of caprylic (8 carbon chain) and capric (10 carbon chain) mono- and diesters of glycerin. Aqueous suspensions comprising the inventive film coating compositions, methods of applying the coatings to substrates and the coated substrates themselves are also disclosed.
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