Systems and methods for gas turbine combustion profile monitoring are disclosed. In one embodiment, a method for detecting an anomaly in a combustion section of a gas turbine is disclosed. The method includes receiving, from a plurality of thermal sensors disposed around an exhaust section of a gas turbine, exhaust profile data of the gas turbine. The method further analyzes the exhaust profile data to calculate statistical features associated with a peak-trough pattern. The method further determines, using a machine learning algorithm, that the statistical features are abnormal. In response to the determination, the method processes the exhaust profile data for a predetermined period of time and reports an anomaly in a combustion section of the gas turbine if the statistical features remain abnormal for the predetermined period of time.