A modulation processing method, a UE and a base station are disclosed; wherein, the base station transmits a high-layer configuration signaling to the UE, wherein the high-layer configuration signaling is used to indicate whether to support a high-order Quadrature Amplitude Modulation (QAM) modulation scheme, wherein the high-order QAM modulation scheme is a modulation scheme of M QAM, wherein M is a number greater than 64. With a high-layer configuration signaling indicating whether to support the high-order QAM, the high-order QAM modulation scheme is supported on the basis of being compatible with existing wireless transmission networks, and the peak data rate and the spectral efficiency are improved