A system, methods, and interfaces for managing request routing functionality associated with resource requests for one or more resources associated with a content provider. The request routing functionality can correspond to the processing of domain name service (“DNS”) requests for resources by computing devices and the resolution of the DNS requests by the identification of a network address of a computing device that will provide the requested resources. Unlike traditional CDN service provider implementation, the processing of resource requests by the service provider is separate from the delivery of the content by the content provider (or on behalf of the content provider).