A method of transmitting an uplink reference signal of a user equipment (UE) in a multi-node system is described. The method according to an embodiment includes receiving a synchronization signal from a node; receiving a parameter for a virtual cell identifier (ID) from the node; generating an uplink demodulation reference signal (DM-RS) using the parameter for the virtual cell ID; and transmitting the generated uplink DM-RS to the node. A physical cell ID is a cell ID obtained from the synchronization signal, and the parameter for the virtual cell ID is a parameter used for generating the uplink DM-RS in the replacement of the physical cell ID.