Invention Grant
- Patent Title: High-yield transgenic mammalian expression system for generating virus-like particles
-
Application No.: US14619693Application Date: 2015-02-11
-
Publication No.: US09795666B2Publication Date: 2017-10-24
- Inventor: Pei-Wen Hsiao , Chia-Ying Wu , Yi-Chun Yeh
- Applicant: Academia Sinica
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K39/145
- IPC: A61K39/145 ; C12N7/01 ; A61P31/16 ; A61K39/42 ; C12N15/44 ; A61K39/215 ; C07K14/005 ; A61K39/12 ; C07K16/10 ; G01N33/569 ; A61K39/00
Abstract:
Virus-like particles (VLPs) of mammalian-hosted viruses, such as SARS-CoV and influenza viruses, have been recombinantly produced from Vero cells. The VLPs closely emulate the exterior of authentic virus particles and are highly immunogenic. They can elicit not only humoral but also cellular immune responses in a mammal. Compositions and methods related to the VLPs are also described.
Public/Granted literature
- US20150265697A1 HIGH-YIELD TRANSGENIC MAMMALIAN EXPRESSION SYSTEM FOR GENERATING VIRUS-LIKE PARTICLES Public/Granted day:2015-09-24
Information query
