Invention Grant
- Patent Title: Process for the preparation of benzonorbornenes
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Application No.: US14603857Application Date: 2015-01-23
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Publication No.: US09796646B2Publication Date: 2017-10-24
- Inventor: Denis Gribkov , Bjorn Antelmann , Fanny Giordano , Harald Walter , Alain De Mesmaeker
- Applicant: Syngenta Participations AG
- Applicant Address: US NC Greensboro
- Assignee: Syngenta Crop Protection, LLC
- Current Assignee: Syngenta Crop Protection, LLC
- Current Assignee Address: US NC Greensboro
- Agent R. Kody Jones
- Priority: EP08018721 20081027; EP09161388 20090528
- Main IPC: C07C23/08
- IPC: C07C23/08 ; C07C17/32 ; C07C17/23 ; C07C17/26 ; C07C17/266 ; C07C22/02 ; C07C201/12 ; C07C205/11 ; C07C209/36 ; C07C205/12

Abstract:
The present invention relates to a novel process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ylamine which process comprises a) reacting cyclopentadiene in the presence of a radical initiator and CXCl3, wherein X is chloro or bromo, to a compound of formula II aa) reacting cyclopentadiene with CXCl3, wherein X is chloro, in the presence of a metal catalyst to a compound of formula II wherein X is chloro, b) reacting the compound of formula II with a base in the presence of an appropriate solvent to the compound of formula III c) and converting the compound of formula III in the presence of 1,2-dehydro-6-nitrobenzene to the compound of formula IV and d) hydrogenating the compound of formula IV in the presence of a metal catalyst.
Public/Granted literature
- US20150141712A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES Public/Granted day:2015-05-21
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