- 专利标题： Compounds and compositions as kinase inhibitors
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申请号： US15397787申请日： 2017-01-04
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公开(公告)号： US09809610B2公开(公告)日： 2017-11-07
- 发明人: Matthew T. Burger , Savithri Ramurthy , Benjamin R. Taft
- 申请人： Matthew T. Burger , Savithri Ramurthy , Benjamin R. Taft
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理商 Scott W. Reid
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D213/74 ; C07D413/04 ; C07D413/14 ; A61K31/675 ; C07F9/6558
摘要：
The present invention provides a compound of Formula I: wherein X, Y, Z, R1 and R2 are as described herein, and salts thereof and therapeutic uses of these compounds for treatment of disorders associated with RAF kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.
公开/授权文献
- US20170114083A1 COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS 公开/授权日：2017-04-27
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