A scale suppression apparatus capable of suppressing in a low-priced manner the generation of silica-based scale and calcium-based scale in the influent water containing at least a silica component and a calcium component, a geothermal power generation system using the same, and a scale suppression method are provided. The scale suppression apparatus includes a chelating agent and alkaline agent addition unit injecting liquid containing a chelating agent and an alkaline agent into a pipe arrangement through which influent water such as geothermal water or the like flows, and a controller controlling a pump and a valve of the chelating agent and alkaline agent addition unit. The controller controls the injection of the chelating agent and the alkaline agent and stops of the injection based on the signal output from a scale detection unit for detecting a precipitation state of the scale.