Invention Grant
- Patent Title: Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols
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Application No.: US14902662Application Date: 2014-07-03
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Publication No.: US09815809B2Publication Date: 2017-11-14
- Inventor: Ulla Letinois , Thomas Netscher
- Applicant: DSM IP ASSETS B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: Nixon & Vanderhye P.C.
- Priority: EP13175326 20130705
- International Application: PCT/EP2014/064203 WO 20140703
- International Announcement: WO2015/001029 WO 20150108
- Main IPC: C07D311/00
- IPC: C07D311/00 ; C07D311/22
Abstract:
The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.
Public/Granted literature
- US20160168111A1 FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS Public/Granted day:2016-06-16
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