Disclosed herein are approaches for a precise medication, vitamin, and/or other medication substance organizer having a plurality of storage compartments that house and separate medications and vitamins by a specific time of day and a means for indicating whether a particular medication or vitamin has already been or needs to be taken. This organizer removes doubt associated with missed or duplicate drug dosages, interactions between medications and vitamins, as well as regulating daily medication and vitamin doses. Additionally, the organizer provides a location to indicate a name and a time a medication or vitamin should be ingested or otherwise taken and an indicator to show whether a medication or vitamin has already been removed from the organizer for ingestion. The medication, vitamin, and/or other medication substance organizer can also be used to prompt a user to take medications that will not fit into the organizer, such as an inhaler.