- 专利标题: Substituted pyrazolopyrimidines and method of use
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申请号: US15133851申请日: 2016-04-20
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公开(公告)号: US09828381B2公开(公告)日: 2017-11-28
- 发明人: Ramin Faghih , Achim Moeller , Michael Ochse , Frauke Pohlki , Martin Schmidt , Kevin Sippy , Sean Turner , Elizabeth Louise Van Der Kam
- 申请人: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- 申请人地址: DE Wiesbaden US IL North Chicago
- 专利权人: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- 当前专利权人: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- 当前专利权人地址: DE Wiesbaden US IL North Chicago
- 代理机构: Neal, Gerber & Eisenberg LLP
- 优先权: WOPCT/CN2015/076978 20150420; EP15168924 20150522
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D519/00
摘要:
Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, L1 and G1 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the γ-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
公开/授权文献
- US20160304527A1 SUBSTITUTED PYRAZOLOPYRIMIDINES AND METHOD OF USE 公开/授权日:2016-10-20
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