- 专利标题： Piperidinone carboxamide azaindane CGRP receptor antagonists
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申请号： US15293569申请日： 2016-10-14
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公开(公告)号： US09833448B2公开(公告)日： 2017-12-05
- 发明人: Ian M. Bell , Mark E. Fraley , Steven N. Gallicchio , Anthony Ginnetti , Helen J. Mitchell , Daniel V. Paone , Donnette D. Staas , Cheng Wang , C. Blair Zartman
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理机构： Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 主分类号： A01N43/42
- IPC分类号： A01N43/42 ; A61K31/44 ; A61K31/4545 ; A61K31/435 ; A61K31/438 ; C07D471/10 ; C07D471/20
摘要：
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
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