Invention Grant
- Patent Title: Protein kinase C inhibitors and methods of their use
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Application No.: US15237880Application Date: 2016-08-16
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Publication No.: US09845309B2Publication Date: 2017-12-19
- Inventor: Michael Joseph Luzzio , Julien Papillon , Michael Scott Visser
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Lian Ouyang
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/497 ; C07D413/14
Abstract:
PKC inhibitors are disclosed. The PKC inhibitors are useful for treating PKC associated diseases, including certain cancers. The PKC inhibitors have improved efficacy at lower dosage amounts to achieve tumor regression, improved potency, PK profile, absorption, gastrointestinal tolerance and kinase selectivity.
Public/Granted literature
- US20160347737A1 PROTEIN KINASE C INHIBITORS AND METHODS OF THEIR USE Public/Granted day:2016-12-01
Information query
