发明授权
- 专利标题： Expression vector
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申请号： US14880671申请日： 2015-10-12
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公开(公告)号： US09845475B2公开(公告)日： 2017-12-19
- 发明人: Bhupendra Vallabh Kara , Christopher David John Lennon
- 申请人： FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED
- 申请人地址： GB Billingham
- 专利权人： Fujifilm Diosynth Biotechnologies UK Limited
- 当前专利权人： Fujifilm Diosynth Biotechnologies UK Limited
- 当前专利权人地址： GB Billingham
- 代理机构： Morgan, Lewis & Bockius LLP
- 优先权： GB0810154.5 20080604
- 主分类号： C12N15/70
- IPC分类号： C12N15/70 ; C12N15/62
摘要：
An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
公开/授权文献
- US20160024509A1 Expression Vector 公开/授权日：2016-01-28
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