- 专利标题： Compositions and methods for inhibiting cytochrome P450
-
申请号： US14992534申请日： 2016-01-11
-
公开(公告)号： US09849107B2公开(公告)日： 2017-12-26
- 发明人: Michael Eissenstat , Dehui Duan
- 申请人： SEQUOIA PHARMACEUTICALS, INC.
- 申请人地址： US MD Potomac
- 专利权人： SEQUOIA PHARMACEUTICALS, INC.
- 当前专利权人： SEQUOIA PHARMACEUTICALS, INC.
- 当前专利权人地址： US MD Potomac
- 代理机构： Edell, Shapiro & Finnan, LLC
- 主分类号： A61K31/343
- IPC分类号： A61K31/343 ; A61K31/33 ; A61K31/4155 ; A61K31/4178 ; A61K31/4184 ; A61K31/4196 ; A61K31/427 ; A61K31/4427 ; A61K31/4709 ; A61K45/06 ; A61K31/437 ; A61K31/4433 ; A61K31/4545 ; C07D307/79 ; C07D405/12 ; C07D405/14 ; C07D417/12 ; C07D471/04 ; C07D491/048 ; A61K31/443 ; A61K31/444
摘要：
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.
公开/授权文献
- US20160361287A1 COMPOSITIONS AND METHODS FOR INHIBITING CYTOCHROME P450 公开/授权日：2016-12-15
信息查询
IPC分类:
