Check valves are disclosed that have a housing defining an internal cavity having a first port and a second port both in fluid communication therewith, and having a first seat defined by a first elastomeric V-ring seal and a second seat. and a check valve plate within the internal cavity that is translatable, in response to pressure differentials, between a closed position against the first seat and an open position against the second seat within the internal cavity of the housing. The first elastomeric V-ring seal includes a body having an interference fit to an annular channel defined by the housing and a lip extending from the body in a direction that defines a generally V-shaped void, viewed in cross-section, opening in a direction away from and generally perpendicular to the flow through the elastomeric V-ring seal into the internal cavity.