Invention Grant
- Patent Title: Cationic lipid
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Application No.: US15109512Application Date: 2015-01-07
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Publication No.: US09873669B2Publication Date: 2018-01-23
- Inventor: Yuta Suzuki , Kenji Hyodo , Yohei Tanaka
- Applicant: Eisai R&D Management Co., Ltd. , Sogo Pharmaceutical Co., Ltd.
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.,Sogo Pharmaceutical Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.,Sogo Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Fish & Richardson P.C.
- International Application: PCT/JP2015/050295 WO 20150107
- International Announcement: WO2015/105131 WO 20150716
- Main IPC: C07D211/62
- IPC: C07D211/62 ; A61K47/22 ; A61K9/51 ; C07D205/04 ; C07D207/16 ; C12N15/11 ; A61K48/00 ; C12N15/113

Abstract:
The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.
Public/Granted literature
- US20160326116A1 CATIONIC LIPID Public/Granted day:2016-11-10
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