- 专利标题: Process for the preparation of benzonorbornenes
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申请号: US15717327申请日: 2017-09-27
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公开(公告)号: US09878970B1公开(公告)日: 2018-01-30
- 发明人: Denis Gribkov , Bjorn Antelmann , Fanny Bois , Harald Walter , Alain De Mesmaeker
- 申请人: Syngenta Crop Protection, LLC
- 申请人地址: US NC Greensboro
- 专利权人: Syngenta Crop Protection, LLC
- 当前专利权人: Syngenta Crop Protection, LLC
- 当前专利权人地址: US NC Greensboro
- 代理商 James Cueva
- 优先权: EP08018721 20081027; EP09161388 20090528
- 主分类号: C07C22/02
- IPC分类号: C07C22/02 ; C07C22/04 ; C07C205/06 ; C07C205/11 ; C07C205/12 ; C07C17/32 ; C07C17/266 ; C07C209/36 ; C07C17/23 ; C07C17/26 ; C07C201/12
摘要:
The present invention relates to a novel a process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ylamine which process comprises a) reacting cyclopentadiene in the presence of a radical initiator and CXCl3, wherein X is chloro or bromo, to a compound of formula I1, or aa) reacting cyclopentadiene with CXCl3, wherein X is chloro, in the presence of a metal catalyst to a compound of formula I1, wherein X is chloro, b) reacting the compound of formula I1 with a base in the presence of an appropriate solvent to the compound of formula III, c) and converting the compound of formula III in the presence of 1,2-dehydro-6-nitrobenzene to the compound of formula IV, and d) hydrogenating the compound of formula IV in the presence of a metal catalyst.
公开/授权文献
- US20180016211A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES 公开/授权日:2018-01-18
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