Invention Grant
- Patent Title: Salts of dasatinib in amorphous form
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Application No.: US14906974Application Date: 2014-07-22
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Publication No.: US09884857B2Publication Date: 2018-02-06
- Inventor: Andreas Hafner , Fritz Blatter , Martin Szelagiewicz , Bernd Siebenhaar , Tiziana Chiodo , Tobias Hintermann , Beate Salvador , Marcus Vossen
- Applicant: BASF SE
- Applicant Address: DE
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE
- Agency: Drinker Biddle & Reath LLP
- Priority: EP13178015 20130725
- International Application: PCT/EP2014/065674 WO 20140722
- International Announcement: WO2015/011119 WO 20150129
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D275/06 ; C07D213/80 ; C07C55/12
Abstract:
The present invention primarily relates to salts of Dasatinib, wherein the salts are in amorphous form. The salts described herein preferably comprise a cation of a compound of formula 1 and an anion of a second compound selected from the group consisting of glutaric acid, nicotinic acid and saccharin. The invention is further related to pharmaceutical compositions comprising such a salt. Furthermore, the invention relates to processes for preparing said salts. The invention also relates to several aspects of using said salt or pharmaceutical composition to treat a disease.
Public/Granted literature
- US20160168142A1 SALTS OF DASATINIB IN AMORPHOUS FORM Public/Granted day:2016-06-16
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