Invention Grant
- Patent Title: Methods of treatment with bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1
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Application No.: US15214160Application Date: 2016-07-19
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Publication No.: US09884919B2Publication Date: 2018-02-06
- Inventor: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
- Applicant: GENENTECH, INC.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Baker Botts L.L.P.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/40 ; C07K14/71 ; C07K16/28 ; A61K39/00
Abstract:
The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
Public/Granted literature
- US20160319038A1 ANTIBODIES AND METHODS OF USE Public/Granted day:2016-11-03
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