A user profile layer provides a benefit to a user by allowing access to user profile setting and data across multiple information handling systems running one or more operating systems. Operating system specific data may be stored in a user profile operating system layer while user data may be stored in a user profile data layer. Each time a user logs in to an information handling system, a layering driver captures changes to user data and to user settings corresponding to the operating system. A new user profile operating system layer is created for each type of operating system associated with a user while only one user profile data layer is maintained for the same user. In this way, any changes made to the same operating system data or user data are captured by the user's specific user profile and usable each time the user logs in to any information handling system.