A vehicle control system includes a brake system onboard a vehicle, a first actuation component, an automatic control system, and a second actuation component. The first actuation component is operably coupled to the brake system and is configured to cause actuation of the brake system to brake the vehicle when the first actuation component is activated. The automatic control system is onboard the vehicle and is configured to generate a first control signal for controlling the first actuation component to activate to upon occurrence of one or more designated conditions. The second actuation component is operably coupled to the brake system and is configured to cause actuation of the brake system to brake the vehicle upon receipt of one of the first control signal or a second control signal generated by the automatic control system.